Top Fitness Fragen

What are the side effects of epoetin alfa?

More common

  • Bone or joint pain.
  • general feeling of tiredness or weakness.
  • heartburn or belching.
  • itching or stinging at the injection site.
  • loss of strength or energy.
  • muscle aches or weakness.
  • skin pain.
  • stomach discomfort, upset, pain, or swelling.

What is the most common adverse effect of epoetin?

Commonly reported side effects of epoetin alfa include: upper respiratory tract infection, arthralgia, decreased serum iron, diarrhea, edema, fever, low serum ferritin, paresthesia, respiratory congestion, skin rash, tachycardia, cough, dyspnea, headache, nausea, signs and symptoms of injection site, and vomiting.

What are the serious side effects of Epogen?

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

What should be monitored when taking epoetin?

It is very important that your doctor check the blood of you or your child on a regular basis while you are using this medicine. You may also need to monitor your blood pressure at home. If you notice any changes to your recommended blood pressure, call your doctor right away. .

What is the therapeutic effect of epoetin?

Epoetin alfa works by signaling the bone marrow to make more red blood cells. This medication is very similar to the natural substance in your body (erythropoietin) that prevents anemia.

Does erythropoietin have side effects?

The side effects that occur most often with ESA use include: High blood pressure. Swelling. Fever.

Which manifestation is an adverse reaction of erythropoietin?

Rarely, some people have an allergic reaction to erythropoietin. Contact the hospital straight away on the number you have been given if you develop any of the following: red, warm and itchy bumps on the skin (like nettle rash) swelling of the lips, tongue or throat.

What effect would injections of EPO have on a person?

By injecting EPO, athletes aim to increase the number of red blood cells and, consequently, their aerobic capacity. If EPO levels are too high the body will produce too many red blood cells which can thicken the blood, leading to clotting, heart attack and stroke.

How long can you take Epogen?

After 8 weeks of therapy, if there is no response as measured by hemoglobin levels or if RBC transfusions are still required, discontinue Epogen.

Can Epogen cause a stroke?

Discuss the risks and benefits of epoetin alfa with your doctor, as this medication may rarely cause very serious (possibly fatal) side effects, including blood clots, heart attack, stroke, or heart failure.

What vitamin do you take with epoetin alfa?

You may need to eat foods that contain iron, folic acid, or vitamin B12 such as eggs, certain cereals, meats, and vegetables, or you may take an iron, folic acid, or vitamin B12 supplement while you are using this medicine.

What is the fastest way to increase red blood cells?

5 nutrients that increase red blood cell counts

  1. red meat, such as beef.
  2. organ meat, such as kidney and liver.
  3. dark, leafy, green vegetables, such as spinach and kale.
  4. dried fruits, such as prunes and raisins.
  5. beans.
  6. legumes.
  7. egg yolks.

What does epoetin alfa interact with?

Epoetin Alfa has moderate interactions with the following drugs: cyclosporine. dichlorphenamide. methyltestosterone.

Does EPO make you gain weight?

Erythropoietin (Epo) is a pleotropic cytokine with several nonhematopoietic tissue effects. High-dose Epo treatment-mediated effects on body weight, fat mass and glucose tolerance have recently been reported, thus extending its pleotropic effects to fat and glucose metabolism.

What are the contraindications of epoetin alfa?

Epoetin alfa is contraindicated in patients with serious allergic reactions, such as anaphylactic reactions, angioedema, bronchospasm, skin rash, and urticaria, to the product. Immediately and permanently discontinue epoetin alfa and administer appropriate therapy if a hypersensitivity reaction occurs.

How does erythropoietin affect blood pressure?

It is believed that increase in hematocrit and blood viscosity after treatment with recombinant human erythropoietin alters vascular responsiveness and increases vascular resistance, which leads to hypertension [23].

How long do EPO effects last?

Improves 3-K time by 6%; effects last at least four weeks. A new and nicely designed study of EPO’s effect on distance runners has shown that four weeks of every-other-day injections improves 3000-meter running time by an average of 6%.

What are two conditions that cause polycythemia?

Apparent polycythaemia is often caused by being overweight, smoking, drinking too much alcohol or taking certain medicines – including diuretics (tablets for high blood pressure that make you pee more). Apparent polycythaemia may improve if the underlying cause is identified and managed.

How long does erythropoietin stay in your system?

EPO is undetectable in urine after 3–4 days of injection.

What happens if you have too much erythropoietin?

Excess erythropoietin results from chronic exposure to low oxygen levels or from rare tumours that produce high levels of erythropoietin. It causes a condition known as polycythaemia which means high red blood cell count. In many people, polycythaemia does not cause any symptoms.

What are the contraindications of epoetin alfa?

Epoetin alfa is contraindicated in patients with serious allergic reactions, such as anaphylactic reactions, angioedema, bronchospasm, skin rash, and urticaria, to the product. Immediately and permanently discontinue epoetin alfa and administer appropriate therapy if a hypersensitivity reaction occurs.

Why does erythropoietin cause hypertension?

It is believed that increase in hematocrit and blood viscosity after treatment with recombinant human erythropoietin alters vascular responsiveness and increases vascular resistance, which leads to hypertension [23].

Does epoetin alfa affect blood pressure?

Chronic administration of erythropoietin (EPO) is associated with an increase in arterial blood pressure in patients and animals with chronic renal failure (CRF). Several mechanisms have been considered in the pathogenesis of EPO-induced hypertension.

What should I monitor with Epogen?

Your doctor will test your blood regularly—at least weekly at the beginning of your treatment—to make sure EPOGEN® is working. The test will measure your Hb or your hematocrit (hee-MAT-a-crit) levels, though most doctors measure Hb because it is a better way to check for anemia.

Can Epogen cause a stroke?

Discuss the risks and benefits of epoetin alfa with your doctor, as this medication may rarely cause very serious (possibly fatal) side effects, including blood clots, heart attack, stroke, or heart failure.